Enhanced Imc for Glucose Control in Type I Diabetic Patients

Maintaining the glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study, the Enhanced Internal Model Controller (EIMC) is developed for a diabetic, due to its simple structure, better disturbance attenuation and uncertainty reduction capabilities. A first order plus time delay (FOTD) model approximation of nominal patient model is used for developing the EIMC. The controller performance is assessed based on its ability to track normoglycemic set point (81.1 mg/dl) in response to a 50 g meal disturbance. In the nominal case, the controller maintains the glucose concentration within 6.5 mg/dl of set point. The robustness of the controller is studied by application to a fairly "diverse" group of "patients", and compared with that of IMC controller. Copyright © 2004 IFAC.